The Microbes Missing
From Modern Diets

115 unintended victims of widespread food sterilization.

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Peer Reviewed Science

As academics, GB's founders have been researching microbial ecosystems for the last 10 years. Our research was funded by the NIH and NSF, and has been published in some of the most prestigious journals on the planet including Nature, Science, and PlosOne.

Evolutionary Nutrition

In a natural environment your digestive ecosystem's holes are filled by a constant influx of microbes already digesting the food you eat. In the modern world, these microbes are dead on arrival.

Equilibrium's strains were selected to directly restore the unintended victims of widespread food sterilization. It provides a microbial intake significantly closer to the environment our digestions evolved for.

Profound Results

Our 200 person, placebo-controlled study is coming soon! Below are the results from our pilot study:

  • All participants who previously experienced post-meal discomfort reported a substantial reduction or complete relief.
  • 81% of participants reported a noticeable improvement in digestive function
  • 72% of participants reported a reduction in food cravings and mild weight loss
  • 54% of participants reported an increase in alertness and energy
  • 45% of participants reported reduced stress levels

Design Overview

Modern food is missing the microbes we evolved eating

They’ve been sterilized away.

Our fruits, vegetables, meats, nuts, grains – almost all our food – would be microbially unrecognizable to our ancestors. Our stomachs didn’t evolve in this environment.

Dietary microbes are required for normal digestive function

Healthy digestion is powered by a complex ecosystem, over 50 trillion microbial cells from 1,500 different strains. Aging, antibiotics, infection, and poor food choices can permanently destroy our strains, leaving holes in the ecosystem’s function.

In a natural environment your digestive ecosystem’s holes are filled by a constant influx of microbes already digesting the food you eat. In the modern world, these microbes are dead on arrival.

On average, modern humans to have less than half as many digestive strains as our ancestors.

Traditional probiotics don’t provide the missing strains

Most probiotics are simply large doses of the yeasts used to make bread, and the bacteria used to make yogurt. These aren’t the strains missing from our diets.

Until recently there was little that could be done. Sterilization is a necessity until better farming techniques can be found. It’s the best known method to protect against food-borne illness.

Equilibrium restores the dietary microbes lost as a by-product of widespread food sterilization

This product is a direct offshoot of our founder’s offshoot of our founder’s participation in the NIH’s Human Microbiome Project, a $115 million dollar census of humanity’s gut flora. The data tells a clear story: as a society our digestive flora is dying off, and this lack of diversity has causal links to western stomach issues.

Using our datasets, we identified the strain groups commonly missing from western microbiomes. We then worked backwards from this data to locate missing dietary microbes which provide the needed function.

What does evolutionarily normal digestion feel like?

  • It’s alert and focused. Similar to the difference between a full night’s sleep and missing an hour or two.
  • It’s relaxed. We are now big believers in the published correlations between happiness, stress, and a diverse microbiome.
  • It’s better at digesting. We no longer worry about the “after effects” of our food choices.

In short: It’s nice. You’ll notice the difference.

Ready to experience evolutionarily normal digestion?

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Do you have more questions about Equilibrium? See our FAQ, or email us at questions@generalbiotics.com

Are you interested in learning more about your microbiome? See our science section for an overview.


GB’s founders are scientists. As academics, our research on microbial ecosystems was funded by the NIH and NSF, and has been published in some of the most prestigious journals on the planet including Nature, Proceedings of the National Academy of Science, and PlosOne.

For company information see our mission, and ethics sections.


  • probiotics (115 strains in their natural ratios, 1 billion CFUs)
  • prebiotic (ground organic flax seed)
  • delayed release capsules (plant derived hypromellose)

Hypromellose is an ingredient used in gluten free bread. It is well studied, inert / non-toxic, and in our opinion is the safest known solution for delayed release capsules.

Contains trace amounts of soy, 20 parts per million (0.002%) or less gluten.

Contains no dairy, eggs, fish, shellfish, gelatin, nuts, wheat, casein, MSG, stearates (including magnesium stearate), GMO, artificial color or flavors.

Caution: As with any food or dietary supplement, consult your doctor before using this product, especially if you are nursing, pregnant, plan to become pregnant, are immunocompromised, under active health supervision, or anticipate surgery.

Disclaimer: This product is a nutritional supplement, and is solely intended to help you increase your microbial intake.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Although our scientists have performed NIH and NSF funded research, and have been published in Nature, Science, and PlosOne, these organizations do not necessarily endorse this specific product.

1 Billion CFU from 115 strains that no other probiotic supplement offers.

Shelf stable, no refrigeration required.

Delayed release capsules for proper delivery.

Small, easy to swallow capsules.

Designed in California, grown in the United States.

100% recyclable bottle, 100% compostable capsules.

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